With the International Network of Excellence (INE) Program, the Leducq Foundation looks to support original and outstanding research in the areas of cardiovascular and neurovascular disease. Applicants are encouraged to think innovatively and to propose bold new ideas. Leducq Foundation accepts applications in basic, translational, and clinical science, including collaborative “bench to bedside and back” programs. Applicants should aim for results that, at the conclusion of the five-year term, have the potential to advance the diagnosis, management, or prevention of human disease, consistent with the overall mission of the Leducq Foundation.